Endocrine Abstracts

Introduction: The classical revealing manifestations of a pituitary adenoma are represented by the combination of a tumor syndrome and endocrine syndrome. The occurrence of meningoencephalitis as a mode of revelation of a macroadenoma is exceptional.Case: Mr. M.O, 36 years old, with no significant medical history, brutally presented severe headaches, vomiting, behavioral disorder with fever and bilateral decreased visual acuity. On examination, the patie...

Introduction: Venous thrombotic disease is a multicausal disease with many powerful risk factors (genetic, hormonal, environmental …). In recent years, several reports suggest possible relationships between hyperthyroidism and risk of venous thrombosis. We report the case of a patient with hyperthyroidism complicated by pulmonary embolism.Case report: A 43-year-old female patient, who’s under treatment for a relapse of Grave’s disease, sh...

Introduction: Graves’ disease is an autoimmune disease, it is considered to be the most common cause of hyperthyroidism. Autoimmune pluriendocrine syndromes include a diverse group of diseases characterized by functional impairment of at least two endocrine glands due to autoimmune events.Material and methods: This is a retrospective hospital record-based study of patients with Graves’ disease followed up in the day hospital of the department o...

Introduction: Hematological toxicity is considered as the main risk of synthetic antithyroid drugs; its major form consists of acute agranulocytosis which can be lethal and requires urgent and adequate management. We report the case of a patient who developed acute agranulocytosis within 1 month of therapy.Observation: A 24-year-old patient with no particular medical history was admitted for management of hyperthyroidism, with a history of weight loss, p...

Introduction: Central diabetes insipidus (DIC) is defined by the excretion of large volume of diluted urine, secondary to an absolute or relative deficiency of endogenous vasopressin. We report three observations of children with central diabetes insipidus.Results: This study reports the case of three patients whose average age was thirteen years old (11, 13 and 15 y). The occurrence of polyuria-polydipsia syndrome was the main reason for consultation an...

Introduction: Hypoglycemia is rarely due to an auto-immune etiology, which is the presence in the serum of the patient of anti-insulin or anti-insulin receptor antibodies. The present case is of a slow type 1 diabetic patient in whom the autoimmune origin of repeated hypoglycemia was found.Case: A 58 years old female patient, Who is a slow type 1 diabetes carrier, and has been on premixed human insulin for 4 years, the patient presented repeated episodes...

Introduction: The concept of food addiction, which refers to people who exhibit signs of dependence to some high-fat and high-sugar foods, was recently proposed by applying DSM criteria of substance dependence to eating behavior. The Aim of This study is to assess the prevalence of food addiction among obese patients.Material and methods: This is a retrospective hospital record-based study of obese patients followed up in the day hospit...

Introduction: Mixed thyroid carcinoma is an entity that corresponds to tumors with a double component: one of the vesicular type (Tg +) and the other of the medullary type (CT +). We report the occurrence of papillary and medullary thyroid carcinoma in a 44-year-old patient. This coexistence is considered rare.Case: A 44-year-old patient underwent a thyroidectomy due to a goiter, histopathological examination identified multifocal papillary carcinoma, mu...

Introduction: Latent autoimmune diabetes in adults (LADA) is autoimmune diabetes occurring in a subject over 30 years of age with positive anti-island antibodies and insulin therapy after 6 months. Inaugural ketosis is an unusual presentation at the time of diagnosis due to the slow progression of beta cell destruction. The purpose of this work is to point out the different revelation modalities of LADA patientsPatients and methods: A cross-sectional des...

Introduction: The majority of thyroid diseases in adults can also affect the child. Graves’ disease is characterized by the association of signs of hyperthyroidism and exophthalmia. It is a rare condition in pediatrics and especially affects the big child. Easy to diagnose, Graves’ disease in children requires strict management. We report 3 clinical cases of baseline disease, 2 of which required radical treatment.Case 1: A 9-year-old child cons...